USP6 N-terminal-like protein (related to the N-terminus of tre, RN-tre, USP6NL, KIAA0019)

Function

• acts as a GTPase activating protein for RAB5A
• role in receptor trafficking
• in complex with EPS8 inhibits internalization of EGFR
• interacts with EPS8

Structure

• contains 1 Rab-GAP TBC domain

Expression

widely expressed

More general terms

• GTPase-activating protein (GAP)

Database

• OMIM: https://mirror.omim.org/entry/605405
• UniProt: http://www.uniprot.org/uniprot/Q92738.html