neurabin-1; neurabin-I; neural tissue-specific F-actin-binding protein I; protein phosphatase 1 regulatory subunit 9A (PPP1R9A, KIAA1222)

Function

• binds to actin filaments (F-actin) & shows cross- linking activity
• binds along the sides of the F-actin
• may be involved in neurite formation
• inhibits protein phosphatase 1-alpha (putative)
• possibly exists as an homodimer, homotrimer or an homotetramer
• interacts with F-actin, protein phosphatase 1 (PP1), neurabin-2 & p70-S6K (putative)

Structure

• interacts with p70-S6K via its PDZ domain (putative)
• contains 1 PDZ domain (DHR domain)
• contains 1 SAM (sterile alpha motif) domain

Compartment

• cytoplasm, cytoskeleton (putative)
• cell junction, synapse, synaptosome (putative)

Alternative splicing

named isoforms=2

More general terms

• protein phosphatase-1 regulatory subunit
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=55607
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:55607
• OMIM: https://mirror.omim.org/entry/602468
• UniProt: http://www.uniprot.org/uniprot/Q9ULJ8.html