CD213a2; interleukin-13 receptor alpha-2 chain; interleukin-13-binding protein (IL13RA2, IL13R)

Function

• binds as a monomer with high affinity to interleukin 13 (IL-13), but not to IL4
• functions as decoy?

Structure

• the WSXWS motif appears to be necessary for proper protein folding, efficient intracellular transport & cell-surface receptor binding
• the box 1 motif is required for JAK interaction &/or activation
• belongs to the type I cytokine receptor family, type 5 subfamily
• contains 1 fibronectin F3 module

Compartment

membrane

More general terms

• CD antigen
• protein subunit

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3598
• OMIM: https://mirror.omim.org/entry/300130
• UniProt: http://www.uniprot.org/uniprot/Q14627.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3598