WSXWS motif
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Introduction
Associated with 2 disulfide bridges in ligand-binding domain of hematopoietin receptor superfamily proteins. May facilitate hinge region. Tryptophans apparently involved in hydrophobic binding with ligand.
More general terms
Additional terms
References
- ↑ Idzerda RL et al, Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily. J Exp Med 1990 Mar 1;171(3):861-73 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2403843