AML1-ETO fusion protein

From Aaushi
Jump to navigation Jump to search

Introduction

product of translocation t(8;21)(q22;q22), seen in some cases of acute myeloid leukemia, M2 subtype. transcriptional repressor through recruitment of histone deacetylase activity[1]

More general terms

References

  1. 1.0 1.1 Marks et al. Nature Reviews Cancer 1:194-202, 2001