ribonucleoprotein PTB-binding 2 (protein raver-2, RAVER2, KIAA1579)

Function

• may bind single stranded nucleic acids
• interacts with PTBP1 & RAVER1
• phosphorylated upon DNA damage, probably by ATM or ATR

Structure

• Contains 3 RRM domains (RNA recognition motif)

Compartment

• nucleus, cytoplasm
• may shuttle between the nucleus & cytoplasm

Alternative splicing

named isoforms=2

More general terms

• RNA-binding protein
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q9HCJ3.html