cold shock domain-containing protein E1 (UNR protein, N-ras upstream gene protein, CSDE1, D1S155E, KIAA0885, NRU, UNR)

Function

• RNA-binding protein
• translationally coupled mRNA turnover
• interacts with STRAP
• component of complex associated with FOS mCRD domain consisting of PABPC1, PAIP1, HNRPD & SYNCRIP
• interaction with PABPC1 (RNA-independent)

Structure

• contains 9 CSD domains (cold-shock domains)

Compartment

cytoplasm

Alternative splicing

named isoforms=2

Pathology

• internal initiation of translation of human rhinovirus RNA

More general terms

• RNA-binding protein

Database

• OMIM: https://mirror.omim.org/entry/191510
• UniProt: http://www.uniprot.org/uniprot/O75534.html