neurofascin (NFASC, KIAA0756)

Function

• cell adhesion
• ankyrin-binding protein
• neurite extension, axonal guidance, synaptogenesis, myelination & neuron-glial cell interactions (putative)
• component of a neurofascin/NRCAM/ankyrin-G complex (putative)
• associates with the sodium channel beta-1 (SCN1B) beta-3 (SCN3B) subunits
• interacts with GLDN/gliomedin (putative)

Structure

• belongs to the immunoglobulin superfamily L1/neurofascin/NgCAM family
• contains 5 fibronectin F3 domains.
  • contains 6 Ig-like C2-type domains (immunoglobulin-like domains)

Compartment

membrane

More general terms

• glycoprotein
• phosphoprotein
• membrane protein
• immunoglobulin superfamily protein

Database

• UniProt: http://www.uniprot.org/uniprot/O94856.html