syntabulin; syntaxin-1-binding protein; Golgi-localized syntaphilin-related protein (SYBU, GOLSYN, KIAA1472)
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Function
- mediates sorting & transport of syntaxin-cargo vesicles along microtubules in neuronal processes
- interacts with STX1A & KIF5B
Compartment
- isoform 3,4,5: Golgi membrane
- isoform 1 colocalizes with syntaxin vesicles along microtubules in neuronal processes
Alternative splicing
named isoforms=5
Expression
- isoform 3, isoform 4 and isoform 5 are expressed in HeLa cells
- isoform 3 is expressed in fetal & adult brain
- isoform 4 is expressed in numerous fetal tissues (brain, kidney, liver, lung, and thymus) & in adult brain, kidney, liver, lung, pancreas, colon, prostate, small intestine, testis, thymus
- isoform 5 is expressed in brain & small intestine