Ca+2 signal-modulating cyclophilin ligand; CAML (CAMLG, CAML)

Function

• likely role in mobilization of Ca+2 via interaction with TCR/CD3 complex
• binds to cyclophilin B
• the N-terminal domain binds to TNFRSF13B/TACI

Compartment

membrane

Expression

• ubiquitous
• highest expression in brain, testis & ovary

More general terms

• membrane protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=819
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:819
• OMIM: https://mirror.omim.org/entry/601118
• UniProt: http://www.uniprot.org/uniprot/P49069.html