nicastrin (NCSTN, KIAA0253, UNQ1874/PRO4317)

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Function

Structure

Compartment

Alternative splicing

named isoforms=2

Expression

Pathology

More general terms

Component of

References

  1. Yu G, Nishimura M, Arawaka S, Levitan D, Zhang L, Tandon A, Song YQ, Rogaeva E, Chen F, Kawarai T, Supala A, Levesque L, Yu H, Yang DS, Holmes E, Milman P, Liang Y, Zhang DM, Xu DH, Sato C, Rogaev E, Smith M, Janus C, Zhang Y, Aebersold R, Farrer LS, Sorbi S, Bruni A, Fraser P, St George-Hyslop P. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature. 2000 Sep 7;407(6800):48-54. PMID: https://www.ncbi.nlm.nih.gov/pubmed/10993067
  2. Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23385
  3. UniProt http://www.uniprot.org/uniprot/Q92542.html

Database