SCO-spondin (SSPO)

Function

• role in modulation of neuronal aggregation
• role in developmental events during formation of the central nervous system

Structure

• belongs to the thrombospondin family
• contains 1 CTCK domain (C-terminal cystine knot-like domain)
• contains 2 EGF-like domains
• contains 1 EMI domain
• contains 1 F5/8 type C domain
• contains 10 LDL-receptor class A domains
• contains 6 TIL domains (trypsin inhibitory-like domains)
• contains 24 TSP type-1 domains
• contains 3 VWFC domains
• contains 3 VWFD domains

Compartment

secreted

More general terms

• secreted protein
• glycoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/A2VEC9.html