WD repeat protein 44 (rabphilin-11 WDR44)

Function

• downstream effector for RAB11
• role in vesicle recycling (putative)
• interacts with GTP-bound form of RAB11 when membrane- associated
• does not bind to other Rab & Rho small G proteins

Structure

contains 7 WD repeats

Compartment

• cytoplasm, perinuclear region, endosomal membrane, trans-Golgi network
• colocalized with RAB11 along microtubules oriented toward lamellipodia

Alternative splicing

named isoforms=3

More general terms

• WD repeat protein family
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/Q5JSH3.html