suppressor of G2 allele of SKP1 homolog (Sgt1, 40-6-3 protein, SUGT1)

Function

• role in ubiquitination & subsequent proteosomal degradation of target proteins
• associates with SCF complex through interaction with SKP1
• interacts with S100A6

Structure

• contains 1 CS domain
• contains 1 SGS domain
• contains 3 TPR repeats

Alternative splicing

named isoforms=2

More general terms

• phosphoprotein

Database

• OMIM: https://mirror.omim.org/entry/604098
• UniProt: http://www.uniprot.org/uniprot/Q9Y2Z0.html