catenin alpha-3; alpha T-catenin; cadherin-associated protein (CTNNA3)

Function

• formation of stretch-resistant cell-cell adhesion complexes
• interacts with CTNNB1

Structure

belongs to the vinculin/alpha-catenin family

Compartment

• cytoplasm, cytoskeleton (putative)
• localizes to intercalated disks of cardiomyocytes & in peritubular myoid cells of testis
• colocalizes with CTNNA1 & CTNNA2

Alternative splicing

named isoforms=2

Expression

• predominantly expressed in heart, testis > brain, kidney, liver, skeletal muscle

More general terms

• alpha catenin
• phosphoprotein
• human longevity protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=29119
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:29119
• OMIM: https://mirror.omim.org/entry/607667
• UniProt: http://www.uniprot.org/uniprot/Q9UI47.html