lymphocyte-specific protein 1; 52 kD phosphoprotein; protein pp52; lymphocyte-specific antigen WP34; 47 kD actin-binding protein (LSP1 WP34)

Function

• may play a role in mediating neutrophil activation & chemotaxis
• phosphorylated by casein kinase 2, protein kinase C & MAPKAPK2
• phosphorylation by PKC induces translocation from membrane to cytoplasm
• phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis
• binds actin

Compartment

• cell membrane
• peripheral membrane protein cytoplasmic side

Expression

expressed in activated T-lymphocytes

More general terms

• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P33241.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4046
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:4046
• OMIM: https://mirror.omim.org/entry/153432