protein kinase C (PKC)

Introduction

A family of proteins

Function

• in vivo, PKC prefers phosphorylation of Ser or Thr found close to a C-terminal basic residue
• additional basic residues at the N- or C-terminal of the target amino acid enhances the Vmax & Km of phosphorylation

Compartment

• apparently localize to focal adhesions

More general terms

• serine/threonine kinase
• allosteric enzyme

More specific terms

• protein kinase (C-mu protein kinase D1, PRKD1, PKD, PKD1, PRKCM)
• protein kinase C type-A
• protein kinase C type-B
• protein kinase C type-D2 (PRKD2, nPKC-D2, HSPC187)
• protein kinase C-nu (protein kinase D3, NPKC-nu, protein kinase EPK2, PRKD3, PRKCN)