protein kinase (C-mu protein kinase D1, PRKD1, PKD, PKD1, PRKCM)

Function

• Ca+2-independent, phospholipid-dependent
• serine/threonine kinase
• interacts via its N-terminal region with CENTA1
• activated by diacylglycerol & phorbol esters
• autophosphorylated (putative)

Structure

• belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKC subfamily
• contains 1 PH domain
• contains 2 phorbol-ester/DAG-type Zn+2 fingers
• contains 1 protein kinase domain

More general terms

• protein kinase C (PKC)
• zinc finger protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q15139.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5587
• OMIM: https://mirror.omim.org/entry/605435
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5587