microtubule-associated protein 1B; MAP-1B; microtubule-associated protein 5; contains: MAP1 light chain LC1 (MAP1B)

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Function

Structure

  • highly basic region with many copies of the sequence KKEE & KKEI/V, repeated but not at fixed intervals, responsible for the binding of MAP1B to microtubules
  • belongs to the MAP1 family

Expression

fetal protein

Pathology

More general terms

References

  1. Hasegawa M et al Immunochemical evidence that fragments of phosphorylated MAP5 (MAP1B) are bound to neurofibrillary tangles in Alzheimer's disease. Neuron 1990 Jun;4(6):909-18 PMID: https://www.ncbi.nlm.nih.gov/pubmed/2361014
  2. Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4131
  3. UniProt http://www.uniprot.org/uniprot/P46821.html

Database