dynamin 1 (DNM1, DNM)

Function

• microtubule-associated GTPase involved in producing microtubule bundles
• involved in vesicular trafficking processes, including endocytosis
• interacts with CAV1 & SH3GLB1
• binds SH3GL1, SH3GL2 & SH3GL3 (putative)

GTP + H2O <--> GDP + phosphate

Structure

• belongs to the dynamin family
• contains 1 GED domain
• contains 1 PH domain

Compartment

cytoplasm, cytoskeleton, microtubule-associated

More general terms

• dynamin
• phosphoprotein

Additional terms

• dynamin-1-like protein; Dnm1p/Vps1p-like protein; DVLP; dynamin family member proline-rich carboxyl-terminal domain less; Dymple; dynamin-like protein; dynamin-like protein 4; dynamin-like protein IV; HdynIV; dynamin-related protein 1 (DNM1L, DLP1, DRP1)

Database

• UniProt: http://www.uniprot.org/uniprot/Q05193.html
• OMIM: https://mirror.omim.org/entry/602377
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1759