aldolase-C (brain-type aldolase, ALDOC, ALDC)

Function

• carbohydrate degradation; glycolysis
• D-glyceraldehyde-3-phosphate & glycerone phosphate from D-glucose: step 4/4
• preference of aldolase C for fructose-1,6-diphosphate & fructose-1-phosphate is intermediate between that of aldolase A & aldolase B

D-fructose 1,6-bisphosphate
            <-->
glycerone phosphate + D-glyceraldehyde 3-phosphate

Structure

• homotetramer
• belongs to the class I fructose-bisphosphate aldolase family

Expression

expressed in brain

More general terms

• fructose-1,6 diphosphate aldolase
• phosphoprotein

Database

• UniProt: http://www.uniprot.org/uniprot/P09972.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:230
• OMIM: https://mirror.omim.org/entry/103870
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=230