inorganic pyrophosphatase 2, mitochondrial; pyrophosphatase SID6-306; pyrophosphate phospho-hydrolase 2; PPase 2 (PPA2)

Function

• pyrophosphatase

Cofactor: Mg+2 (putative)

Structure

• homodimer (putative)
• belongs to the PPase family

Compartment

mitochondria (putative)

Alternative splicing

• named isoforms=4
• at least one isoform may be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay

Expression

• detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood & a cell line derived from kidney proximal tubule epithelium

More general terms

• pyrophosphatase (diphosphohydrolase)
• mitochondrial protein
• metalloprotein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=27068
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:27068
• OMIM: https://mirror.omim.org/entry/609988
• UniProt: http://www.uniprot.org/uniprot/Q9H2U2.html