breast cancer metastasis-suppressor 1-like protein (BRMS1-homolog protein p40, BRMS1-like protein p40, BRMS1L)

Function

• role in the histone deacetylase (HDAC1)-dependent transcriptional repression activity
• when overexpressed in lung cancer cell line that lacks p53/TP53 expression, inhibits cell growth
• component of the Sin3/HDAC1 corepressor complex
• interacts with HDAC & SIN3A

Structure

belongs to the BRMS1 family

Compartment

nucleus (probable)

More general terms

• nuclear protein

Component of

• corepressor complex

Database

• UniProt: http://www.uniprot.org/uniprot/Q5PSV4.html