nuclear receptor interaction protein; NRIP; IQ motif & WD repeat-containing protein 1; androgen receptor complex-associated protein (ARCAP, IQWD1, DCAF6)

Function

• ligand-dependent coactivator of nuclear receptors
• enhances transcriptional activity of the nuclear receptors NR3C1 & AR
• interacts with the nuclear receptors NR3C1 & AR in the presence of ligand

Structure

• contains 1 IQ domain
• contains 7 WD repeats

Compartment

nucleus

Alternative splicing

named isoforms=3

Expression

• highly expressed in skeletal muscle & testis
• expressed to a lesser degree in heart, prostate, & adrenal gland

More general terms

• nuclear protein
• WD repeat protein family

Database

• UniProt: http://www.uniprot.org/uniprot/Q58WW2.html