PDZ domain containing protein 2 (activated in prostate cancer protein, AIPC, KIAA0300, PDZD2)

Function

• interacts with SCN10A, CTNND2 & PKP4

Compartment

• nucleus, endoplasmic reticulum, cytoplasm
• at cell-cell contacts in lung epithelial cells
• the proteolytic processed protein is secreted

Alternative splicing

named isoforms=2

Expression

expressed in prostate

Pathology

• early promotion of prostate cancer (putative)

More general terms

• nuclear protein

Additional terms

• PDZ (PSD-95 post-synaptic density protein, Discs large, Zona occludens tight junction protein) domain
• PDZ domain-containing protein

Database

• UniProt: http://www.uniprot.org/uniprot/O15018.html