inositol hexakisphosphate kinase 2; insP6 kinase 2; P(i)-uptake stimulator; PiUS (IP6K2, IHPK2, TCCCIA00113)

Function

• converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5)
• converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4

Structure

belongs to the inositol phosphokinase (IPK) family

Compartment

nucleus

Alternative splicing

• named isoforms=3
• at least one isoform may be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay

More general terms

• inositol hexaphosphate kinase (IHPK)
• nuclear protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51447
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:51447
• OMIM: https://mirror.omim.org/entry/606992
• UniProt: http://www.uniprot.org/uniprot/Q9UHH9.html