cleavage stimulation factor 77 kD subunit; CSTF 77 kD subunit; CstF-77; CF-1 77 kD subunit (CSTF3)

Function

• one of multiple factors required for polyadenylation & 3'-end cleavage of mammalian pre-mRNAs homodimer
• component of CSTF complex
• CSTF3 directly interacts with CSTF1 & CSTF2
• interacts with FIP1L1

Structure

contains 9 HAT repeats

Compartment

nucleus

More general terms

• protein subunit
• nuclear protein
• phosphoprotein

Component of

• cleavage stimulation factor

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1479
• OMIM: https://mirror.omim.org/entry/600367
• UniProt: http://www.uniprot.org/uniprot/Q12996.html