NF-kappa-B inhibitor-like protein 1 (inhibitor of kappa B-like, I-kappa-B-like, IkappaBL, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1, NFKBIL1, IKBL)

Function

• negative regulator of NF-kappa-B activation (putative)

Structure

• contains 2 ANK repeats

Expression

• detected in different cell types including monocytes, T-cells, B-cells & hepatocytes

Pathology

• mutations in the promoter region of NFKBIL1 represent the 2nd rheumatoid arthritis susceptibility locus within HLA region

More general terms

• other protein

Additional terms

• IKB protein

Database

• OMIM: https://mirror.omim.org/entry/180300
• OMIM: https://mirror.omim.org/entry/601022
• UniProt: http://www.uniprot.org/uniprot/Q9UBC1.html