thyrotroph embryonic factor (TEF)

Function

• transcription factor
• binds to & transactivates the TSHB promoter
• binds to a minimal DNA-binding sequence 5'-[TC][AG][AG]TTA[TC][AG]-3'
• binds DNA as a homodimer or a heterodimer
• can form a heterodimer with DBP
• accumulates according to a robust circadian rhythm

Structure

• belongs to the bZIP family, PAR subfamily
• contains 1 bZIP domain

Compartment

nucleus

More general terms

• other protein

Database

• OMIM: https://mirror.omim.org/entry/188595
• UniProt: http://www.uniprot.org/uniprot/Q10587.html