thyroid-stimulating hormone [TSH]-beta chain (thyrotropin beta chain, TSHB)
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Function
- stimulates thyroid hormone secretion by thyroid
- indispensable for the control of thyroid structure & metabolism
Structure
- heterodimer of a common alpha chain (glycoprotein hormone alpha) & a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin & gonadotropin
- belongs to the glycoprotein hormones subunit beta family
Compartment
Expression
- secreted by thyrotrophs of anterior pituitary as thyrotropin
Pharmacology
More general terms
More specific terms
Component of
References
- ↑ UniProt http://www.uniprot.org/uniprot/P01222.html
- ↑ Clinical information on thyrogen http://www.genzyme.com/thyrogen/pi.htm
- ↑ Wikipedia; thyroid-stimulating hormone entry http://en.wikipedia.org/wiki/thyroid-stimulating_hormone