alpha-catulin (catenin alpha-like protein 1, alpha-catenin-related protein, ACRP, CTNNAL1)

Function

• modulation of Rho pathway signaling
• provides scaffold for Lbc Rho guanine nucleotide exchange factor ARHGEF1 (putative)
• interacts with ARHGEF1

Compartment

• cytoplasm, peripheral membrane protein

Alternative splicing

named isoforms=3

Expression

• widely expressed
• expressed in adrenal gland > neural tissues

Pathology

• down-regulated in pancreatic cancer cells undergoing differentiation & apoptosis

More general terms

• other protein

Database

• OMIM: https://mirror.omim.org/entry/604785
• UniProt: http://www.uniprot.org/uniprot/Q9UBT7.html