protein kinase A2 [PKA2] regulatory subunit-alpha (PRKAR2A)

Function

• type 2 regulatory chain
• may mediate membrane association by binding to anchoring proteins
• interacts with AKAP4 & CBFA2T3
• phosphorylated by the activated catalytic chain

Structure

• belongs to the cAMP-dependent kinase regulatory chain family
• contains 2 cyclic nucleotide-binding domains

Expression

• four types of regulatory chains are found: I-alpha, I-beta, II-alpha, & II-beta
• their expression varies among tissues & is in some cases constitutive & in others inducible

More general terms

• protein kinase A2 regulatory

Additional terms

• protein kinase A2

Database

• UniProt: http://www.uniprot.org/uniprot/P13861.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5576
• OMIM: https://mirror.omim.org/entry/176910