A-kinase anchor protein 4 (protein kinase A-anchoring protein 4, PRKA4, A-kinase anchor protein 82 kD, AKAP 82, hAKAP82, major sperm fibrous sheath protein, HI, AKAP4, AKAP82)

Function

• major structural component of sperm fibrous sheath
• role in sperm motility
• interacts with PRKAR1A & PRKAR2A

Compartment

• ocalizes to principle piece of sperm flagellum

Alternative splicing

named isoforms=3

Expression

• testis specific, only expressed in round spermatids
• post-meiotic phase of spermatogenesis

More general terms

• other protein

Database

• OMIM: https://mirror.omim.org/entry/300185
• UniProt: http://www.uniprot.org/uniprot/Q5JQC9.html