forkhead box protein P4 (FOXP4)
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Function
- transcriptional repressor
- represses lung-specific expression
- forms homodimers & heterodimers with FOXP1 & FOXP2
- dimerization is required for DNA-binding
- leucine-zipper is required for dimerization & transcriptional repression
Structure
- contains 1 C2H2-type zinc finger
- contains 1 fork-head DNA-binding domain