high affinity immunoglobulin epsilon receptor subunit gamma; IgE Fc receptor subunit gamma; FceRI gamma; Fc-epsilon RI-gamma (FCER1G)

Function

• associates with a variety of FcR alpha chains to form a functional signaling complex
• regulates several aspects of the immune response
• component of IgE receptor
• the gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface
• also subunit(s) of other Fc receptors like FCGR1A

Structure

• belongs to the CD3Z/FCER1G family
• contains 1 ITAM domain

Compartment

cell membrane

More general terms

• plasma membrane protein
• protein subunit
• phosphoprotein

Component of

• immunoglobulin E [IgE] receptor or Fc epsilon [IgE] receptor-1

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2207
• OMIM: https://mirror.omim.org/entry/147139
• UniProt: http://www.uniprot.org/uniprot/P30273.html