immunoglobulin-E (IgE)

Introduction

Binds to mast cells.

Mediates type I hypersensitivity reactions (allergy).

50% of IgE is intravascular.

Also present in respiratory & gastrointestinal mucosa.

Laboratory

• IgE in blood
• IgE in CSF
• IgE in nasal fluid
• IgE in serum
  • IgE monoclonal in serum
• IgE in urine

More general terms

• immunoglobulin

Additional terms

• hyperimmunoglobulin E (Job's syndrome)
• IgE in serum
• immunoglobulin E [IgE] receptor or Fc epsilon [IgE] receptor-1
• mast cell
• rhuMAB-E25
• type 4 hypersensitivity; T-cell-mediated (delayed) hypersensitivity

Database

• OMIM: https://mirror.omim.org/entry/147050