enolase (2-phospho-D-glycerate hydrolase)

Structure

• enolase is a dimer of any 2 of 3 peptides, alpha, beta & gamma

Expression

• alpha/alpha homodimer is expressed in embryo & in most adult tissues
• alpha/beta heterodimer & beta/beta homodimer are found in striated muscle
• alpha/gamma heterodimer & the gamma/gamma homodimer are found in neurons

More general terms

• hydro-lyase, hydratase or dehydratase
• oligomerizing protein
• glycolytic enzyme

More specific terms

• enolase alpha, lung specific (ENO1B)
• enolase-1; alpha enolase; phosphopyruvate hydratase; C-myc promoter-binding protein; plasminogen-binding protein (ENO1, ENO1L1, MBPB1, MPB1)
• enolase-2; gamma-enolase; neuron specific enolase (ENO2)
• enolase-3 (ENO3, beta-enolase)
• Enolase-phosphatase E1 (EC 3.1.3.77, 2,3-diketo-5-methylthio-1- phosphopentane phosphatase, MASA homolog) (ENOPH1 MASA MSTP145)

Additional terms

• gluconeogenesis
• glycolytic pathway (glycolysis, Embden Myerhof pathway)

Database

• OMIM: https://mirror.omim.org/entry/172430