chloride intracellular channel 6 (CLIC6, CLIC1L)
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Function
- probable Cl- channel
- may play a critical role in water-secreting cells, possibly through the regulation of Cl- transport (putative)
- interacts with dopamine receptors DRD2, DRD3 & DRD4
- phosphorylated (putative)
Structure
belongs to the chloride channel CLIC family
Compartment
- cytoplasm (putative), cell membrane
- predominantly cytoplasmic
- upon Cl- efflux from the cell, it is translocated to the plasma membrane (putative)
Alternative splicing
named isoforms=2
Expression
expressed in brain, placenta, pancreas & liver