CD49e (integrin alpha-5, integrin alpha-F, fibronection receptor alpha subunit, ITGA5)

Function

• associaties with integrin beta-1 (integrin alpha-5/beta-1)
• interacts with HPS5

Structure

• composed of an heavy & a light chain linked by a disulfide bond
• belongs to the integrin alpha chain family
• contains 7 FG-GAP repeats

Compartment

membrane

Pathology

• interacts with HIV-1 Tat (see VLA-5)

More general terms

• integrin-alpha
• CD antigen

Component of

• very late antigen 5 (VLA-5, integrin alpha-5/beta-1)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3678
• OMIM: https://mirror.omim.org/entry/135620
• UniProt: http://www.uniprot.org/uniprot/P08648.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3678