dystrobrevin beta; DTN-B; beta-dystrobrevin (DTNB)

Function

• interacts with dystrophin short form DP71 & syntrophins SNTG1 & SNTG2
• binds dystrobrevin binding protein 1

Structure

• the coiled coil domain may mediate the interaction with dystrophin
• belongs to the dystrophin family, Dystrobrevin subfamily
• contains 1 ZZ-type Zn+2 finger

Compartment

• cytoplasm

Alternative splicing

• named isoforms=4
• additional isoforms seem to exist
• at least pne isoform may be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay

Expression

• highly expressed in brain, kidney & pancreas

More general terms

• dystrobrevin
• zinc finger protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1838
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1838
• OMIM: https://mirror.omim.org/entry/602415
• UniProt: http://www.uniprot.org/uniprot/O60941.html