rhoN protein (Rho-related GTP-binding protein RhoN, Rho7, Rnd2)

Function

• may be specifically involved in neuronal & hepatic functions
• C3 toxin-insensitive member of the Rho subfamily
• interacts with the Rho-GAP domain of RACGAP1
• interacts with UBXD5

Structure

belongs to the small GTPase superfamily, Rho family

Compartment

• cell membrane; lipid-anchor; cytoplasmic side (putative
• colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles & the acrosome

Expression

highly expressed in testis

More general terms

• rho subfamily protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=8153
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:8153
• OMIM: https://mirror.omim.org/entry/601555
• UniProt: http://www.uniprot.org/uniprot/P52198.html