UBX domain-containing protein 5; Socius; colorectal tumor-associated antigen COA-1 (UBXD5, UBXN11, SOC, PP2243)

Function

• role in reorganization of actin cytoskeleton mediated by RND1, RND2 & RND3 (putative)
• promotes RHOA activation mediated by GNA12 & GNA13
• interacts with GNA12, GNA13, RND1, RND2 & RND3

Structure

contains 1 UBX domain

Compartment

cytoplasm

Alternative splicing

named isoforms=8

Polymorphism

• number of repeats is polymorphic & varies from 1-4

More general terms

• UBX domain-containing protein (UBXD)

Database

• UniProt: http://www.uniprot.org/uniprot/Q5T124.html