G13-alpha (GNA13)
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Function
- G-alpha subunit of G protein
- interacts with UBXD5
- palmitoylation required for proper membrane localization & signaling
- phosphorylation on Thr-203 by PKA destabilizes the heterotrimer of alpha, beta & gamma, & inhibits Rho activation
Structure
belongs to the G12-alpha family
Compartment
membrane, lipid-anchor, melanosome
More general terms
Additional terms
References
- ↑ Simon et al, Diversity of G proteins in signal transduction. Science 252:802 1991 PMID: https://www.ncbi.nlm.nih.gov/pubmed/1902986
- ↑ UniProt http://www.uniprot.org/uniprot/Q14344.html