thrombospondin-3 (THBS3, TSP3)

Function

• adhesive glycoprotein
• mediates cell-to-cell & cell-to-matrix interactions
• can bind to fibrinogen, fibronectin, laminin & type 5 collagen

Structure

• oligomer; disulfide-linked
• belongs to the thrombospondin family
• contains 4 EGF-like domains
• contains 1 TSP C-terminal (TSPC) domain
• contains 1 TSP N-terminal (TSPN) domain
• contains 8 TSP type-3 repeats

More general terms

• thrombospondin
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7059
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7059
• OMIM: https://mirror.omim.org/entry/188062
• UniProt: http://www.uniprot.org/uniprot/P49746.html