AP-2 complex subunit beta-1; adapter-related protein complex 2 beta-1 subunit; beta2-adaptin; beta-adaptin; plasma membrane adaptor HA2/AP2 adaptin beta subunit; clathrin assembly protein complex 2 beta large chain; AP105B (AP2B1, ADTB2, CLAPB1)

Function

• component of clathrin-associated adaptor protein complex 2 (AP-2)
• binds EPN1, EPS15, SNAP91 & clathrin

Structure

• belongs to the adaptor complexes large subunit family

Compartment

• cell membrane, coated pit
• peripheral membrane, cytoplasmic side
• component ofthe coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane

Alternative splicing

named isoforms=2

More general terms

• beta adaptin (adaptor-related protein complex, beta subunit)
• phosphoprotein

Additional terms

• clathrin (triskelion)

Component of

• HA2/AP2 adaptor complex

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:163
• OMIM: https://mirror.omim.org/entry/601025
• UniProt: http://www.uniprot.org/uniprot/P63010.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=163