ephrin-B2; EPH-related receptor tyrosine kinase ligand 5; LERK-5; HTK ligand; HTK-L (EFNB2, EPLG5, HTKL, LERK5)

Function

• binds to the receptor tyrosine kinases EPHB4 & EPHA3
• may play a role in constraining the orientation of longitudinally projecting axons (putative)
• inducible phosphorylation of Tyr in the cytoplasmic domain (putative)
• interacts with PDZRN3 (putative)
• binds to Nipah virus G protein

Structure

• belongs to the ephrin family

Compartment

• membrane; single-pass type 1 membrane protein

Expression

expressed in lung & kidney

More general terms

• ephrin B or ephrin B ligand

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1948
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1948
• OMIM: https://mirror.omim.org/entry/600527
• UniProt: http://www.uniprot.org/uniprot/P52799.html