hypermethylated in cancer 2 protein; Hic-2; Hic-3; HIC1-related gene on chromosome 22 protein; zinc finger & BTB domain-containing protein 30 (HIC2, HIC3, ZBTB30, HRG22, KIAA1020)

Function

• transcriptional repressor
• interacts with CtBP
• interacts with HIC1

Structure

• self-associates
• belongs to the krueppel C2H2-type Zn+2-finger protein family, Hic subfamily
• contains 1 BTB/POZ domain
• contains 5 C2H2-type Zn+2 fingers

Compartment

nucleus

Alternative splicing

named isoforms=2

Expression

highest levels in cerebellum

More general terms

• C2H2 type zinc finger protein
• nuclear protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23119
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:23119
• OMIM: https://mirror.omim.org/entry/607712
• UniProt: http://www.uniprot.org/uniprot/Q96JB3.html