homeobox protein HMX1 (homeobox protein H6, HMX1, H6)

Function

• DNA-binding protein
• binds to the 5'-CAAG-3' core sequence
• may function as a transcriptional repressor
• transcriptional antagonist of NKX2-5 (putative)
• role in the development of craniofacial structures, including eye & ear

Structure

• belongs to the HMX homeobox family
• contains 1 homeobox DNA-binding domain

Compartment

nucleus

More general terms

• homeobox protein
• DNA-binding protein

Database

• OMIM: https://mirror.omim.org/entry/142992
• UniProt: http://www.uniprot.org/uniprot/Q9NP08.html