DNA repair protein RAD51 homolog 3; R51H3; RAD51-like protein 2 (RAD51C RAD51L2)

Function

• role in homologous recombination repair pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents
• the RAD51B-RAD51C dimer exhibits single-stranded DNA dependent ATPase activity
• component of the BCDX2 complex
• interacts with RAD51B & XRCC3
• part of a complex with RAD51B & RAD51

Structure

belongs to the recA family, RAD51 subfamily

Compartment

nucleus (probable)

Expression

• expressed in a variety of tissues, with highest expression in testis, heart muscle, spleen & prostate

More general terms

• DNA repair protein Rad51 homolog

Component of

• BCDX2 complex

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5889
• OMIM: https://mirror.omim.org/entry/602774
• UniProt: http://www.uniprot.org/uniprot/O43502.html