TGF-beta-activated kinase 1 & MAP3K7-binding protein 1; mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1 (TAB1, MAP3K7IP1)

Function

• signaling intermediate between TGFB receptors & MAP3K7 (putative)
• interacts with MAP3K7 & BIRC7
• interacts with TRAF6 & MAP3K7 during IL-1 signaling
• may play a role in mammalian embryogenesis

Structure

contains 1 PP2C-like domain

Expression

ubiquitous

More general terms

• MAP3K7 interacting protein
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10454
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:10454
• OMIM: https://mirror.omim.org/entry/602615
• UniProt: http://www.uniprot.org/uniprot/Q15750.html